The role of bats as reservoir hosts of emerging neuroviruses : chapter from Neurotropic viral infections : volume 2: Neurotropic retroviruses, DNA viruses, immunity and transmission

Mackenzie, J S

The role of bats as reservoir hosts of emerging neuroviruses : chapter from Neurotropic viral infections : volume 2: Neurotropic retroviruses, DNA viruses, immunity and transmission - Switzerland : Springer, 2016

Recent studies have clearly shown that bats are the reservoir hosts of a wide diversity of novel viruses with representatives from most of the known animal virus families. In many respects bats make ideal reservoir hosts for viruses: they are the only mammals that fly, thus assisting in virus dispersal; they roost in large numbers, thus aiding transmission cycles; some bats hibernate over winter, thus providing a mechanism for viruses to persist between seasons; and genetic factors may play a role in the ability of bats to host viruses without resulting in clinical disease. This chapter presents the physiological and ecological factors affecting the ability of bats to act as reservoirs of neurotropic viruses, and describes the major transmission cycles leading to human infection.

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