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Gastric Perforation in a Cocaine User

By: Contributor(s): Publication details: 2010Uniform titles:
  • Gastroenterology & Hepatology
Online resources: Summary: Cocaine is one of the alkaloids found in the leaves of the <em>Erythroxylon coca</em> plant. It acts at the syn-aptic terminals, where it reduces the neurotrans-mitter uptake of dopamine and norepinephrine, and it can have many systemic effects. Cocaine is an increasingly used recreational drug in the United Kingdom, with nearly 344,000 individuals estimated to have used this drug.<sup><a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033545/?report=classic#B1" class="bibr popnode tag_hotlink tag_tooltip jig-ncbipopper" id="__tag_209860463">1</a></sup> It can be taken orally, nasally, or parenterally. Crack is a base-free form of cocaine that can be smoked, as heating does not destroy it. In this case report, a patient who developed a gastric perforation associated with smoking cocaine is presented.
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Cocaine is one of the alkaloids found in the leaves of the &lt;em&gt;Erythroxylon coca&lt;/em&gt; plant. It acts at the syn-aptic terminals, where it reduces the neurotrans-mitter uptake of dopamine and norepinephrine, and it can have many systemic effects. Cocaine is an increasingly used recreational drug in the United Kingdom, with nearly 344,000 individuals estimated to have used this drug.&lt;sup&gt;&lt;a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033545/?report=classic#B1" class="bibr popnode tag_hotlink tag_tooltip jig-ncbipopper" id="__tag_209860463"&gt;1&lt;/a&gt;&lt;/sup&gt; It can be taken orally, nasally, or parenterally. Crack is a base-free form of cocaine that can be smoked, as heating does not destroy it. In this case report, a patient who developed a gastric perforation associated with smoking cocaine is presented.

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