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Necrotising external otitis caused by Aspergillus wentii: a case report

By: Contributor(s): Publication details: 2011Uniform titles:
  • Mycoses
Online resources: Summary: <span style="font-family: 'Times New Roman'; font-size: 8pt;"><span class="highlight" style="line-height: 17.999801635742188px;">Necrotising</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">external</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">otitis</span><span style="line-height: 17.999801635742188px;">&nbsp;(NEO) is a destructive, potentially fatal, infection usually seen in elderly diabetics or the immunocompromised. The commonest causative organism is Pseudomonas but immunocompromised patients are additionally susceptible to opportunistic infections. Here we describe the first reported&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">case</span><span style="line-height: 17.999801635742188px;">&nbsp;of NEO&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">caused</span><span style="line-height: 17.999801635742188px;">&nbsp;by a previously unknown human pathogen--</span><span class="highlight" style="line-height: 17.999801635742188px;">Aspergillus</span><span style="line-height: 17.999801635742188px;">&nbsp;</span><span class="highlight" style="line-height: 17.999801635742188px;">wentii</span><span style="line-height: 17.999801635742188px;">. A review of the literature reveals that fungal NEO is associated with a high rate of cranial nerve palsies suggesting that infections are not being treated rapidly enough to prevent morbidity. Fungal infection should be considered early in immunocompromised patients and microbiological diagnosis should be obtained wherever possible.</span></span>
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&lt;span style="font-family: 'Times New Roman'; font-size: 8pt;"&gt;&lt;span class="highlight" style="line-height: 17.999801635742188px;"&gt;Necrotising&lt;/span&gt;&lt;span style="line-height: 17.999801635742188px;"&gt;&amp;nbsp;&lt;/span&gt;&lt;span class="highlight" style="line-height: 17.999801635742188px;"&gt;external&lt;/span&gt;&lt;span style="line-height: 17.999801635742188px;"&gt;&amp;nbsp;&lt;/span&gt;&lt;span class="highlight" style="line-height: 17.999801635742188px;"&gt;otitis&lt;/span&gt;&lt;span style="line-height: 17.999801635742188px;"&gt;&amp;nbsp;(NEO) is a destructive, potentially fatal, infection usually seen in elderly diabetics or the immunocompromised. The commonest causative organism is Pseudomonas but immunocompromised patients are additionally susceptible to opportunistic infections. Here we describe the first reported&amp;nbsp;&lt;/span&gt;&lt;span class="highlight" style="line-height: 17.999801635742188px;"&gt;case&lt;/span&gt;&lt;span style="line-height: 17.999801635742188px;"&gt;&amp;nbsp;of NEO&amp;nbsp;&lt;/span&gt;&lt;span class="highlight" style="line-height: 17.999801635742188px;"&gt;caused&lt;/span&gt;&lt;span style="line-height: 17.999801635742188px;"&gt;&amp;nbsp;by a previously unknown human pathogen--&lt;/span&gt;&lt;span class="highlight" style="line-height: 17.999801635742188px;"&gt;Aspergillus&lt;/span&gt;&lt;span style="line-height: 17.999801635742188px;"&gt;&amp;nbsp;&lt;/span&gt;&lt;span class="highlight" style="line-height: 17.999801635742188px;"&gt;wentii&lt;/span&gt;&lt;span style="line-height: 17.999801635742188px;"&gt;. A review of the literature reveals that fungal NEO is associated with a high rate of cranial nerve palsies suggesting that infections are not being treated rapidly enough to prevent morbidity. Fungal infection should be considered early in immunocompromised patients and microbiological diagnosis should be obtained wherever possible.&lt;/span&gt;&lt;/span&gt;

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