TY - BOOK AU - Shaarawy, Tarek AU - Sherwood, Mark B. AU - Hitchings, R.A. AU - Crowston, Jonathan G. TI - Glaucoma SN - 9780702055416 PY - 2015/// CY - London PB - Elsevier/Saunders N1 - V.I. Section 1: Glaucoma in the world. Prevalence and Geographic Variations -- Screening for glaucoma -- Economics of glaucoma care -- Glaucoma care in different societies -- Section 2: Pathogenesis. Aqueous humor outflow pathways -- Aqueous humor dynamics and intraocular pressure elevation -- Pathogenesis of glaucomatous optic neuropathy -- Mechanical strain and restructuring of the optic nerve head -- Role of vascular blood flow in the pathogenesis of glaucoma -- Section 3: Evaluation of glaucoma. Tonometry and intraocular pressure fluctuation -- Visual fields -- Long term follow-up visual fields -- Function specific perimetry -- Electrophysiology in glaucoma assessment -- Gonioscopy -- Ultrasound biomicroscopy -- Angle imaging: ultrasound biomicroscopy and anterior segment optical coherence tomography -- The impact of central corneal thickness and corneal biomechanics on tonometry -- Optic disc photography in the diagnosis of glaucoma -- Optic disc imaging -- Retinal nerve fiber layer photography and computer analysis -- Structure and function relationships in glaucoma -- Measuring glaucoma progression in clinical practice -- Techniques used for evaluation of ocular blood flow -- Genetics of glaucoma -- Genetic epidemiology -- Section 4: Types of glaucoma. Definitions: what is glaucoma worldwide? -- Ocular hypertension -- Primary open-angle glaucoma -- Primary angle-closure glaucoma -- Exfoliation syndrome and exfoliative glaucoma -- Iridotomy for pigmentary glaucoma -- Normal tension glaucoma -- Childhood glaucomas -- Secondary angle-closure glaucoma -- Uveitic glaucoma -- Neovascular glaucoma -- Other secondary glaucomas -- Post-traumatic glaucomas -- Glaucoma and intraocular tumors -- Glaucoma in the phakomatoses and related conditions -- Section 5: Principles of management. Overview of management of ocular hypertension and primary open-angle glaucoma -- Management of normal tension glaucoma -- An overview of angle-closure management -- Target intraocular pressure -- Quality of life -- Medical management of glaucoma: cost-effectiveness -- Optimizing quality of life: low-vision rehabilitation in glaucoma -- Ocular hypotensive medications: adherence and persistence -- Outcomes -- Benefit versus risk -- Section 6: Medical therapy. Prostagladin analogues -- Beta-blockers -- Carbonic anhydrase inhibitors -- Alpha agonists -- Parasympathomimetics -- Fixed combination therapies in glaucoma -- Ocular surface disease and role preservatives free drops -- Section 7: Emergency care management. Acute intraocular pressure rise -- Glaucoma secondary to trauma -- Section 8: New horizons. Neuroprotection and neuroregeneration -- Interpreting clinical studies on glaucoma neuroprotection -- Stem cells: a future glaucoma therapy -- Gene therapy in glaucoma -- Ultrastructural imaging --;V. II. Section 9: Introduction. Economics of surgery worldwide: developed countries -- When to perform glaucoma surgery -- Economics of surgery worldwide: developing countries -- Lowering intraocular pressure: surgery versus medications -- The trabecular meshwork outflow pathways: surgical aspects -- Section 10: Laser therapy. Selective laser trabeculoplasty -- Peripheral iridotomy for angle-closure glaucoma -- Laser peripheral iridoplasty -- Section 11: Trabeculectomy. Preoperative evaluation and diagnostic approach -- Preoperative conjunctival health and trabeculectomy outcome -- Ophthalmic anesthesia -- Trabeculectomy -- Wound healing and bleb evaluation after trabeculectomy -- Intraoperative complications of trabeculectomy -- Early postoperative increase in intraocular pressure -- Postoperative shallow anterior chamber -- Choroidal effusion -- Trabeculectomy related corneal complications -- Aqueous misdirection -- Late failure of filtering bleb -- Late bleb leaks -- Blebitis and endophthalmitis -- Late hypotony -- Cataract following trabeculectomy -- Section 12: Modulation of wound healing. Risk factors for excess wound healing -- Choice of antifibrosis therapies -- Technique -- Complications associated with modulation of wound healing in glaucoma surgery -- Biological drivers of postoperative scarring -- Future strategies -- Section 13: Non-penetrating glaucoma surgery. Principle and mechanism of function -- Deep sclerectomy -- Viscocanalostomy -- Complications of nonpenetrating glaucoma surgery -- Postoperative management of nonpenetrating glaucoma surgery -- Results of NPGs -- Section 14: Management of co-existing cataract and glaucoma. Cataract surgery in open angle glaucoma -- Cataract surgery closed angle design -- Cataract surgery in patients with functioning filtering blebs -- One-site combined surgery/two-site combined surgery -- Combined cataract extraction and glaucoma drainage implant surgery -- Combined cataract and non-penetrating glaucoma surgery -- Goniosynechialysis -- Section 15: Drainage devices. Preoperative evaluation of patients undergoing drainage implant surgery -- Aqueous shunts: choice of implant -- Surgical technique (Molteno glaucoma implant) -- Surgical technique (Baerveldt glaucoma implant) -- Surgical technique (Ahmed glaucoma valve drainage implant) -- Other glaucoma implants -- Intraoperative complications -- Postoperative complications -- Glaucoma implants: results -- Aqueous shunts after retinal surgery -- Aqueous shunts and keratoplasty -- Section 16: Surgery for congenital glaucoma -- Goniotomy and trabeculotomy -- Further surgical options in children -- Section 17: Cyclodestructive procedures. Cyclodestructive techniques -- Endophotocoagulation -- Complications of cyclodestructive procedures -- Section 18: devices in development and new procedures. trabectome -- The Ex-PRESS miniature glaucoma implant -- Canaloplasty -- Devices in development and new procedures N2 - As the irreversible effects of glaucoma can lead to blindness, there is high demand for early diagnosis and an ongoing need for practitioners to adopt new and evolving medical and surgical treatment options to improve patient outcomes. Glaucoma, Second Edition is the most comprehensive text and online resource in the field delivering expert guidance for the most timely and effective diagnosis and treatment of glaucoma - aimed at specialists, fellows and general ophthalmologists. More than 300 contributors from six continents provide a truly global perspective and explore new approaches in this user friendly reference which has been updated with enhanced images, more spotlights, new videos, and more UR - https://go.openathens.net/redirector/nhs?url=https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C20111045629 ER -