TY - BOOK AU - Hall,Madison R. TI - Head and neck cancer: epidemiology, management and treatment outcomes T2 - Cancer etiology, diagnosis and treatments SN - 9781634821148 PY - 2015///] CY - New York PB - Nova Biomedical KW - Head KW - Cancer KW - Epidemiology KW - Treatment KW - Neck KW - Head and Neck Neoplasms KW - etiology KW - diagnosis KW - therapy N1 - Includes bibliographical references and index; Chapter 1: Management of Mucositis in Head and Neck Cancer Patients; Abstract; Introduction; Clinical Course and Impact of OM; Assessment of Mucositis; Mucositis Prevention; Mucositis-Associated Pain; Opioid Use for Management of Mucositis-Associated Pain; Adjuvant Analgesic Therapies; Nutrition, Hydration and Electrolyte Support during Treatment; Conclusion and Future Directions; 2.2. Downstream Signaling Pathways of HER22.3. Gene Amplification, Protein Overexpression and Mutation of HER2; 3. The Significance of HER2 in; Head and Neck Cancer Treatment; 4. Specific Drugs Targeting HER2; 4.1. Monoclonal Antibodies; 4.2. Tyrosine Kinase Inhibitors; 4.2.1. Lapatinib; 4.2.2. Afatinib; 4.2.3. Dacomitinib; 5. Clinical Trials on HER2 in Head and Neck Cancer; Conclusion; References; Chapter 4: Current Trends and Management in Head and Neck Cancers; Abstract; 1. Head and Neck Squamous Cell Carcinoma; 3. Pathogenesis of Head and Neck Cancers; (i) p53 Pathway N2 - Over 50,000 new cases of head and neck cancer are diagnosed each year in the United States. The majority of these are squamous cell carcinoma (HNSCC), associated with human papillomavirus infection and carcinogenic behaviors such as tobacco use and alcohol consumption. Although these are more common, there are several other causes that this book addresses. This book examines the epidemiology of head and neck cancer. It discusses the management of head neck cancer as well as treatment outcomes UR - https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=993181 ER -