TY - BOOK AU - Gluckman,Peter D. AU - Beedle,Alan AU - Buklijas,Tatjana AU - Low,Felicia AU - Hanson,Mark A. TI - Principles of evolutionary medicine SN - 9780191823206 PY - 2016/// CY - Oxford PB - Oxford University Press KW - Medicine KW - Philosophy KW - Human evolution KW - Diseases KW - Causes and theories of causation KW - Evolution (Biology) KW - Medical genetics KW - Medical personnel KW - Biology KW - Life sciences KW - Physical sciences KW - Biological Evolution KW - Genetics, Medical KW - Genetic Phenomena KW - Genetics KW - Biological Phenomena KW - Health Occupations KW - Phenomena and Processes KW - Disciplines and Occupations KW - Biological Science Disciplines KW - Natural Science Disciplines KW - Philosophy, Medical KW - Health Personnel KW - Health Workforce N1 - This edition previously issued in print: 2016; Includes bibliographical references and index; Cover; Principles of Evolutionary Medicine; Copyright; Contents; PART 1 Fundamentals of Evolutionary Biology ; 1 Introduction ; 1.1 What is disease? ; 1.2 What evolution is: fundamental principles ; 1.3 Time ; 1.4 Constraints ; 1.5 We are not alone ; 1.6 Culture and gene- culture coevolution; 1.7 How evolutionary arguments fit alongside other biological perspectives 1.8 Evolution and medicine ; Key points ; 2 Evolutionary theory ; 2.1 Introduction ; 2.2 What does evolutionary theory explain? ; 2.3 How does evolution work?; 2.4 Areas of debate and the limitations of the adaptationist argument 2.5 Conclusion ; Key points ; 3 The molecular basis of variation and inheritance ; 3.1 Introduction ; 3.2 Genes and disease ; 3.3. The molecular basis of human genetic variation; 3.4 Factors affecting genetic variation 3.5 Single-gene or Mendelian disorders; 3.6 No single genes for common diseases ; 3.7 Epigenetic mechanisms as a cause of variation ; 3.8 Non-genetic inheritance; 3.9 Conclusion ; Key points ; 4 Evolution and development ; 4.1 Introduction; 4.2 Development: pre- ordained or plastic? 4.3 Is development important to evolution? ; 4.4 Developmental plasticity ; 4.5 Responses to environmental cues during development ; 4.6 Epigenetic processes and development ; 4.7 Learning and instinct ; 4.8 The evolution of novelty N2 - This is the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology UR - https://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=1243115 ER -