TY  - BOOK
AU  - Khaku,Aunali S.
TI  - Acute strokes: signs, symptoms and management 
T2  - Cardiology Research and Clinical Developments Ser
SN  - 1536174130
PY  - 2020///]
CY  - New York
PB  - Nova Science Publishers, Inc.
KW  - Cerebrovascular disease
KW  - Treatment
KW  - Brain
KW  - Congestion
KW  - Stroke
KW  - Cerebrovascular Disorders
N1  - Includes bibliographical references and index; Intro -- Contents -- Preface -- Chapter 1 -- Approach to Acute Stroke in the Emergency Setting -- Abstract -- Case Presentation -- Differential Diagnosis -- Definition -- History -- Physical Examination -- Emergency Department Workup -- Vital Signs -- Clinical Investigations -- Labs -- Neuroimaging -- Other Studies -- Administration of rtPA -- rtPA Administration -- Disposition -- Pearls and Pitfalls -- Conflict of Interests -- References -- Chapter 2 -- Acute Secondary Prevention: Preventing Early Recurrence Following -- Ischemic Stroke -- Abstract -- Introduction -- Medical Management; Antiplatelet Agents -- Anticoagulants -- Cholesterol-Lowering Medications -- Blood Pressure Management -- Surgical Management -- Conclusion -- References -- Chapter 3 -- Neuroimaging of Acute Stroke -- Abstract -- Introduction -- Ischemic Stroke -- Noncontrast CT Imaging -- CT Perfusion Imaging -- MRI -- DWI -- FLAIR -- Susceptibility Weighted Imaging (SWI) -- Hemorrhagic Transformation -- Hemorrhagic Stroke -- Sinus Thrombosis -- Dural Arteriovenous Fistula -- Subarachnoid Hemorrhage -- References -- Chapter 4 -- Intravenous Thrombolysis of Acute -- Ischemic Stroke -- Abstract -- Introduction; NINDS -- ECASS III -- IST-3 -- Indications, Dosage, Exclusions, and Complications -- Expanding the Time Window for Intravenous Thrombolysis -- Alternative Agents to Alteplase -- Tenecteplase -- Desmoteplase -- Ancrod -- Glycoprotein IIb/IIIa Antagonists -- Argatroban -- Sonothrombolysis -- References -- Chapter 5 -- Endovascular Management of -- Acute Ischemic Stroke -- Abstract -- Introduction -- Concept of Re-Perfusion -- First Generation Mechanical Thrombectomy Trials -- Newer Generation Mechanical Thrombectomy Trials -- Factors Responsible for Success of New Generation Trials; Patient Selection in First 6 Hours -- Mechanical Thrombectomy in Extended Time Window -- Patient Selection for Mechanical Thrombectomy in Extended Time Window -- Mechanical Thrombectomy in Posterior -- Circulation Strokes -- Technical Aspects of Mechanical Thrombectomy -- Tandem Occlusion -- Anesthetic Care and Management of Hemodynamics -- During the Thrombectomy -- Future Directions -- Conclusion -- References -- Chapter 6 -- Medical Management of Acute Ischemic Stroke -- Abstract -- Introduction -- Pre-Hospital -- Emergency Department (ED) -- Medical Treatments -- Blood Pressure; Hypertension -- Hypotension -- Blood Glucose -- Hyperglycemia -- Hypoglycemia -- Body Temperature -- Antiplatelet Agents -- Aspirin -- Ticagrelor -- Dual Antiplatelet Therapy (DAPT) -- Aspirin- Extended Release Dipyridamole Dual Therapy -- Triple Antiplatelet Therapy -- Anticoagulation in the Acute Setting -- Atrial Fibrillation -- Hyperlipidemia -- Complications after Acute Ischemic Stroke -- References -- Chapter 7 -- Hemorrhagic Stroke -- Abstract -- Etiology and Risk Factors -- Pathophysiology -- Clinical Features -- Diagnosis -- Treatment -- Blood Pressure Management -- Coagulopathy Reversal
N2  - "Stroke is a leading cause of mortality and morbidity worldwide. Just a decade ago, stroke management was simple. Apart from secondary prevention, and education, there was not much a clinician could do that would significantly change outcomes. There were no acute interventions, no tPA, and no endovascular therapies. Stroke was thus not an emergency. Today, we live in a different world. With the advent of tPA and endovascular intervention, acute stroke is an emergency of epic proportions. Time literally is brain and the clinician has to be acutely aware of the advances in stroke in order to maximize the therapeutic impact. Many books have been written about stroke. The authors and editors envisioned a succinct, yet comprehensive guide for the clinician in the management of stroke. From the medical management of stroke, to neuroimaging, thrombolysis, endovascular therapies, and rehabilitation, this book guides the novice clinician as well as the seasoned vascular neurologist to be able to recognize, manage, and treat acute stroke to the best of medical science's guidelines"--
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