TY - BOOK AU - Blum,William AU - Mathews,Vikram TI - Acute myeloid leukemia T2 - Fast facts SN - 9781910797600 (PDF ebook) : PY - 2018/// CY - Abingdon, Oxford PB - Health Press KW - Acute myeloid leukemia KW - Leukemia, Myeloid, Acute N1 - Also issued in print: 2018; Includes bibliographical references and index; Specialized N2 - This last year has seen the approval of the first targeted treatments for acute myeloid leukemia (AML) - following decades with no new developments and a poor prognosis for most patients with the disease. The new drugs reflect the remarkable progress that has been made in our understanding of the pathophysiology of AML and its underlying cytogenetic and molecular abnormalities - which differ not only between patients but also within a patient over time and with treatment. This books provides a comprehensive yet concise foundation for understanding AML - from basic epidemiology, diagnosis, classification and the current 'standard' treatment, through to recent advances in our understanding of the cytogenetic and molecular underpinnings of the disease, such as the IDH2 mutation, and the future for tailored therapy UR - https://app.kortext.com/Shibboleth.sso/Login?entityID=https://idp.eng.nhs.uk/openathens&target=https://app.kortext.com/borrow/2133319 ER -