Brody's human pharmacology: mechanism-based therapeutics

Section 1: Mechanisms of drug action and therapeutic principles. -- Introduction, terminology -- Pharmacodynamics: drug targets (receptors, enzymes, DNA, etc) -- Pharmacokinetics -- Pharmacogenomics -- Drug discovery, development, and regulation -- Section 2: Chemical mediators and drugs affecting autonomic and neuromuscular synapses. -- Introduction to the peripheral nervous systems and drugs for peripheral disorders -- Cholinergic drugs -- Muscarinic agonists and their clinical uses -- Muscarinic antagonists and their clinical uses -- Nicotinic agonists and their clinical uses -- Nicotinic antagonists and neuromuscular blocking drugs -- Adrenergic drugs -- Adrenergic agonists and their clinical uses -- Adrenergic antagonists and their clinical uses -- Section 3: Drug treatment for disorders affecting the central nervous system. Introduction to the CNS and drugs affecting the brain -- Neurodegenerative disorders -- Drug therapy for Alzheimer's disease and other cognitive disorders/dementias -- Pharmacotherapy of basal ganglia disorders: Parkinson's disease and Huntington's disease -- Drug therapy for psychoses and bipolar disorder -- Drug therapy for depression and anxiety -- Drug therapy for the management of attention deficit hyperactivity disorder -- Drug therapy for insomnia and the hypersomnias -- Drug therapy for managing obesity and eating disorders -- Treatment of seizure disorders -- Drug therapy to control spasticity disorders -- Ethanol, other alcohols, and drugs for alcohol use disorder -- Illicit psychoactive compounds and substance use disorder -- Section 4: Drug therapy for pain management. Introduction -- General anesthetics -- Local anesthetics -- Opioid analgesics -- Nonsteroidal anti-inflammatory agents and acetaminophen -- Cannabinoids -- Section 5: Treatment of inflammatory, allergic and immunologic disorders. Drug therapy for migraine headache -- Drug therapy for gout and hyperuricemia -- Drug treatment for allergic reactions -- Immunosuppressants for autoimmune disorders and organ transplantation -- Drug therapy for rheumatoid arthritis -- Section 6: Drug treatment for cardiovascular diseases. Introduction to the cardiovascular system and the regulation of blood pressure and heart rate -- Overview of hypertension management and drugs that decrease sympathetic tone -- Diuretics and drugs that affect volume and electrolyte content -- Drugs affecting the renin-angiotensin-aldosterone system -- Calcium channel blockers -- Vasodilators -- Drug therapy for hyperlipidemias and atherosclerotic cardiovascular disease -- Drug therapy for myocardial ischemia and angina pectoris -- Treatment of heart failure: cardiac glycosides, phosphodiesterase inhibitors and other agents -- Antiarrhythmic drugs -- Anticoagulant, antiplatelet and thrombolytic agents -- Drug therapy for hemophilia and the anemias --;Section 7: Treatment of endocrine disorders. Introduction to endocrine pharmacology -- Treatment of hypothalamic and pituitary disorders -- Treatment of adrenalcorticosteroid disorders -- Female hormone regulation -- Androgens, antiandrogens and their clinical uses -- Drug therapy for the management of diabetes -- Drug therapy for the management of thyroid disorders -- Calcium regulating hormones and agents affecting bone -- Section 8: Chemotherapy. Infectious diseases -- Principles of antimicrobial use -- Bacterial cell wall synthesis inhibitors -- Inhibitors of protein synthesis -- Drugs that target DNA -- Antimycobacterial drugs and the treatment of tuberculosis and leprosy -- Drug therapy for resistant organisms -- Parasitic diseases -- Antifungal agents -- Antimalarial and other antiprotozoal agents -- Antihelmintics -- Viruses -- Drug therapy for non-HIV viral infections -- Drugs for HIV and related opportunistic infections -- Cancer -- Introduction and therapeutic principles -- Cytotoxic agents -- Targeted agents -- Section 9: Special considerations. Therapeutic use of hematopoietic growth factors, vitamins and minerals -- Gastrointestinal disorders and their treatment -- Pharmacological treatment of asthma and COPD -- The role of neutraceuticals and natural products -- Essentials of toxicology -- Therapeutic considerations for pregnant, pediatric, geriatric and obese individuals."