000 04335cam a2200301 4500
001 9780323291774
008 220107t2015 xxu||||| |||| 00| 0 eng d
020 _a9780323291774
020 _a9780323291774
041 _aeng
100 _aOrkin, Stuart H.
245 0 _aNathan and Oski's hematology and oncology of infancy and childhood
250 _a8th ed.
260 _aPhiladelphia :
_bElsevier/Saunders,
_c2015
300 _a1 online resource:illustrations (chiefly color)
490 _aExpertconsult
505 _aAnatomy and physiology of hematopoiesis -- The neonatal erythrocyte and its disorders -- Immune hemolytic disease -- Neonatal jaundice and disorders of bilirubin metabolism -- Hemostasis in the newborn and infant -- Acquired aplastic anemia and pure red cell aplasia -- Inherited bone marrow failure syndromes -- Principles of bone marrow and stem cell transplantation -- Diagnostic approach to the anemic patient -- Megaloblastic anemia -- Disorders of iron and copper metabolism, the sideroblastic anemias, and lead toxicity -- Porphyrias -- Autoimmune hemolytic anemia -- Paroxysmal nocturnal hemoglobinuria -- Red cell membrane -- Disorders of the red cell membrane -- Pyruvate kinase deficiency and disorders of glycolysis -- Glucose-6-phosphate dehydrogenase deficiency -- Normal and abnormal hemoglobins -- Sickle cell disease -- Thalassemias -- Phagocyte system and disorders of granulopoiesis and granulocyte function -- Immune response -- Primary immunodeficiency diseases -- Lysosomal storage diseases -- Platelets and the vessel wall -- Blood coagulation -- Molecular basis of fibrinolysis -- Approach to the child with a suspected bleeding disorder -- Inherited platelet disorders -- Hemophilia and von Willebrand disease -- Rare hereditary coagulation factor abnormalities -- Inherited disorders of thrombosis and fibrinolysis -- Acquired platelet defects -- Acquired disorders of hemostasis -- Transfusion medicine -- Hematologic manifestations of systemic diseases -- Hematologic manifestations of systemic diseases in children of the developing world -- Origins and evolution of pediatric cancers -- Epidemiology of leukemia in childhood -- Informatics -- Genetic predisposition to cancer -- Genetics and epigenetics of childhood cancers -- Targeted therapies in oncology -- Cytogenetic and molecular pathology of pediatric cancer -- Cancer chemotherapy for pediatric patients -- Immunotherapy of cancer -- Pediatric radiation oncology -- Pediatric surgical oncology -- Acute lymphoblastic leukemia -- Pediatric myeloid leukemia, myelodysplasia, and myeloproliferative disease -- Infant leukemias -- Pediatric lymphoma -- Neuroblastoma -- Pediatric renal tumors -- Retinoblastoma -- Tumors of the brain and spinal cord -- Hepatoblastoma and other liver tumors in children -- Rhabdomyosarcoma -- Nonrhabdomyosarcoma soft tissue sarcomas and other soft tissue tumors -- Ewing sarcoma -- Osteosarcoma -- Pediatric germ cell tumors -- Histiocytoses -- Rare tumors of childhood -- Imaging in the evaluation and management of childhood cancer -- Infectious disease in the pediatric cancer patient -- Oncologic emergencies -- Nursing care of patients with childhood cancer -- Palliative care in pediatric oncology -- Symptom management in children with cancer -- Childhood cancer survivorship -- Psychosocial care of the child and family -- Ethical considerations in pediatric oncology clinical trials -- Reference values in infancy and childhood.
520 _aNathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, it brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. -- Publisher.
690 _aPediatric hematology.
690 _aTumors in children.
700 _aFisher, David E.
700 _aGinsburg, David
700 _aLook, A.Thomas
700 _aLux, Samuel E.
700 _aNathan, David G.
856 _uhttps://go.openathens.net/redirector/nhs?url=https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C20120011015
999 _c57668
_d57668