000			04321cam a2200325 4500
001			9780470988398
008			180406t2004 xxu||||| |||| 00| 0 eng d
020			_a9780470988398
020			_a1405107804
020			_a0470988398
020			_a1405140208
020			_a9781405140201
020			_a1280199660
020			_a9781280199660
020			_a1405107804
020			_a9781405107808
100			_aOkpala, Iheanyi E.
245		0	_aPractical management of haemoglobinopathies _h[E-Book]
260			_aMalden, Mass. : _bBlackwell Pub., _c2004
300			_a1 online resource (xi, 244 pages) : illustrations (some color)
505			_atext
505			_aThe concept of comprehensive care of sickle cell disease / I.E. Okpala -- Haemoglobinopathy diagnostic tests (1): blood counts, sickle solubility test, haemoglobin electrophoresis, & high performance liquid chromatography / Yvonne Daniel -- Haemoglobinopathy diagnostic tests (2): isoelectric focusing, mass spectrometry, & DNA analysis / Barbara Wild -- Epidemiology, genetics and pathophysiology of sickle cell disease / I.E. Okpala -- The genetics & multiple phenotypes of beta-thalassaemia / Swee Lay Thein -- The diagnosis & significance of alpha-thalassaemia / A. Stephens -- Morbid anatomy & autopsy findings in sickle cell disease & sickle cell trait / Sebastian Lucas -- Sickle cell crisis / I.E. Okpala -- Treatment modalities for pain in sickle cell disease / I.E. Okpala -- Childhood sickle cell disease & thalassaemia / Moira Dick.
505			_aAcute chest syndrome in sickle cell disease / Josh Wright -- Blood transfusion therapy for haemoglobinopathies / Nay Win -- Management of pregnancy in sickle cell disease & thalassaemia / Susan Bewley -- Hepato-biliary complications of the sickle cell diseases / C.S. Johnson -- Pulmonary hypertension / I.E. Okpala -- Stroke in sickle cell disease / Kwaku Ohene-Frempong -- Clinical management of beta-thalassaemia / Kornelia Cinkotai -- Iron chelation therapy in thalassaemia & sickle cell disease / B. Wonke -- Renal disease in sickle cell disease / Ian Abbs -- Assessment of prognosis & hydroxyurea therapy in sickle cell disease / I.E. Okpala.
505			_aHaemopoietic stem cell transplantation for thalassaemia & sickle cell disease / Irene Roberts & Christina Halsey -- Practical guidelines, antibiotic therapy, exchange blood transfusion / I.E. Okpala -- Drug dependence in sickle cell disease / I.K. Azuonye -- The roles & function of a community sickle cell & thalassaemia centre / C. Rochester-Peart -- Community nursing care for people with thalassaemia & sickle cell disease / Sadie Daley -- Counselling people affected by sickle cell disease & thalassaemia / C. Onyedinma-Ndubueze -- Sickle cell disease & thalassaemia: the challenge for health professionals / Elizabeth Anionwu.
520			_aRemote
520			_aIncludes bibliographical references and index.
520			_aThough knowledge of thalassaemia and sickle cell disease has improved steadily for half a century, these inherited haemoglobulinopathies still present a highly significant public health challenge, particularly in the developing world. Though some important advances in specific therapies such as stem cell transplantation have increased the potential for a cure, improvements in daily management remain central to improving the quality of life of patients. This is a postgraduate text, which will be invaluable to trainees and residents in haematology, haematologists in practice and healthcare professionals treating those with sickle cell disease and thalassaemia. The contributors cover basic science and epidemiological aspects of the public health challenge, but maintain a focus on the day to day issues encountered in dealing with affected people. A comprehensive picture of care management is presented, including diagnostic, therapeutic, and psychosocial aspects. Also included is a separate section of self-assessment questions designed to help candidates prepare for examinations in haematology.; Containing clear, practical advice, this text is an essential, practical resource to bridge the gap between expensive reference texts and smaller manuals.
710			_aWiley InterScience (Online service)
856			_uhttp://dx.doi.org/10.1002/9780470988398 _y[Wiley Online Library]
999			_c57730 _d57730