| 000 | 04555cam a2200517Mu 4500 | ||
|---|---|---|---|
| 001 | ocn966464118 | ||
| 003 | OCoLC | ||
| 005 | 20221128213309.0 | ||
| 006 | m d | ||
| 007 | cr |n|---||||| | ||
| 008 | 161224s2016 xx o 000 0 eng d | ||
| 040 |
_aEBLCP _beng _epn _cEBLCP _dOCLCQ _dN$T |
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| 020 |
_a9781681083476 _q(electronic bk.) |
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| 020 |
_a1681083477 _q(electronic bk.) |
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| 035 |
_a1511884 _b(N$T) |
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| 035 | _a(OCoLC)966464118 | ||
| 072 | 7 |
_aHEA _x039000 _2bisacsh |
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| 072 | 7 |
_aMED _x014000 _2bisacsh |
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| 072 | 7 |
_aMED _x022000 _2bisacsh |
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| 072 | 7 |
_aMED _x112000 _2bisacsh |
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| 072 | 7 |
_aMED _x045000 _2bisacsh |
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| 049 | _aMAIN | ||
| 245 | 0 | 0 |
_aCancer metastasis and cancer stem cellniche _h[electronic resource] / _c |
| 260 |
_aSharjah : _bBentham Science Publishers, _c2016. |
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| 300 | _a1 online resource (157 pages) | ||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 588 | 0 | _aPrint version record. | |
| 505 | 0 | _aFOREWORD ; PREFACE ; Biography ; List of Contributors ; Fundamental Relationships Between Cancer Stem Cells, the Cancer Stem Cell Niche and Metastasis ; INTRODUCTION; FEATURES OF STEMNESS; Stem Cells in Normal Physiology and Development; The Cancer Stem Cell Phenotype; Morphology, Differentiation and Self Renewal; Mitotic Activity; Protein and Biomarker Expression; Metabolism; Metastasis Initiating Cells; Critical Components of Metastasis; Epithelial-to-Mesenchymal Transition; Mechanisms of Metastasis; Contributions of the Niche; The Normal Stem Cell Niche; The CSC Niche. | |
| 505 | 8 | _aThe Metastatic NicheCONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Regulation of Cell Surface Glycan Expression in Cancer Stem Cells ; INTRODUCTION; CANCER STEM CELLS AND EPIGENETIC SILENCING OF GLYCOGENES; Induction of Typical Cancer-associated Glycans Through Epigenetic Silencing of Glycan-related Genes Responsible for Synthesis of Normal Glycans; Mechanisms for Epigenetic Silencing of Glycan-related Genes During the Course of Carcinogenesis; Differentiation-dependent Expression of Glycans in Normal Tissue Stem Cells. | |
| 505 | 8 | _aENHANCED STEMNESS AND ALTERED GLYCAN EXPRESSION BY TUMOR HYPOXIAAcquisition of Resistance to Hypoxia by Cancer Cells in Advanced Stage of Cancers; Normal Stem Cells and Their Hypoxic Niches; STEM CELLS AND GLYCAN ALTERATION IN EPITHELIO-MESENCHYMAL TRANSITION; Glycan Alteration in Epithelio-mesenchymal Transition of Cancer Cells; Normal Stem Cells and Plasticity to Undergo EMT/MET; GLYCANS ASSOCIATED WITH HUMAN EMBRYONIC STEM CELLS AND CANCER STEM CELLS; Appearance of Classical Human Embryonic Stem Cell Marker Glycans, SSEA-3/-4, in Cancer Stem Cells. | |
| 505 | 8 | _aLactoseries Glycans Recently Emerging as Human Embryonic and Cancer Stem Cell MarkersCONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Tumor Endothelial Cells and Cancer Progression ; TUMOR ANGIOGENESIS; TUMOR BLOOD VESSELS ARE MORPHOLOGICALLY ABNORMAL; DIFFERENCES BETWEEN TUMOR ENDOTHELIAL CELLS AND NORMAL ENDOTHELIAL CELLS; HETEROGENEITY OF NORMAL ENDOTHELIAL CELLS; TEC HETEROGENEITY; DRUG RESISTANCE AND CYTOGENETIC ABNORMALITIES IN HM-TECS; MECHANISMS OF TEC HETEROGENEITY; CONCLUSION; FUNDING; DISCLOSURE; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES. | |
| 505 | 8 | _aMetastatic Cancer Stem Cell Niche and the Toll-like Receptor 4 (TLR4)-mediated Premetastatic Microenvironment I. OVERVIEW; I-a. Outline of Tumor Metastasis; I-b. Traffic Accident Theory; I-c. Organ Tropism of Tumor Metastasis; I-d. Pre-metastatic Phase; II. CANCER STEM CELL, RECENT PROGRESS; II-a. Definition of Cancer Stem Cell; II-b. Metastatic Stem Cell; II-c. Cancer Stem Cell and Markers; II-d. Cancer Stem Cells and EMT (Epithelial-mesenchymal Transition); II-e. Tumor Heterogeneity; III. CANCER STEM CELL MODELS; III-a. Clonal Evolution Model; III-b. Classical Cancer Stem Cell Model. | |
| 500 | _aIII-c. Plastic Cancer Stem Cell Model. | ||
| 590 | _aMaster record variable field(s) change: 050, 072, 082, 650 | ||
| 650 | 0 | _aMetastasis. | |
| 650 | 0 | _aCancer. | |
| 650 | 0 | _aStem cells. | |
| 700 | 1 | _aKawaguchi, Takanori. | |
| 856 | 4 | 0 |
_uhttps://search.ebscohost.com/login.aspx?custid=ns123844&authtype=ip,shib&direct=true&scope=site&db=nlebk&db=nlabk&AN=1511884 _yKingston Hospital NHS Foundation Trust OpenAthens account holders click here for access |
| 938 |
_aEBL - Ebook Library _bEBLB _nEBL4768343 |
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| 938 |
_aEBSCOhost _bEBSC _n1511884 |
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| 942 | _n0 | ||
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_a92 _bN$T |
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| 999 |
_c92801 _d92801 |
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